Description

Cannabidiol β-D-Glucuronide is a major, water-soluble metabolite of cannabidiol (CBD), formed via glucuronidation in the liver. This compound is of critical importance for research and development in analytical chemistry and pharmacology, serving as a key reference standard. It is primarily needed by pharmaceutical R&D laboratories, clinical toxicology facilities, and manufacturers of diagnostic kits for the accurate quantification and metabolic profiling of CBD in biological matrices.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the calibration and validation of analytical methods such as LC-MS/MS, HPLC-UV, and GC-MS in bioanalysis.
• Pharmacokinetic & Metabolic Studies: Essential for investigating the absorption, distribution, metabolism, and excretion (ADME) profiles of Cannabidiol in preclinical and clinical research.
• Forensic & Clinical Toxicology: Used to develop and confirm assays for detecting and quantifying CBD consumption in drug testing programs, workplace screenings, and post-mortem analyses.
• Drug Development & Biomarker Research: Serves as a critical tool in the development of new CBD-based pharmaceuticals and in the discovery of metabolic biomarkers.
• Quality Control for Pharmaceutical Manufacturing: Employed in the in-process testing and final release of CBD-derived pharmaceutical products to ensure batch consistency and purity.
• Academic & Institutional Research: Supports fundamental research in cannabinoid science, including studies on metabolism, drug-drug interactions, and enzymatic activity.

Basic Information

Product Name	Cannabidiol β-D-Glucuronide
CAS No.	63958-86-1
Molecular Formula	C27H38O8
Molecular Weight	490.59 g/mol
Synonyms	(-)-Cannabidiol β-D-Glucuronide; CBD-Glucuronide; Cannabidiol Glucuronide; 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-phenylene β-D-Glucopyranosiduronic Acid; 5-Pentyl-2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]benzene-1,3-diyl β-D-Glucopyranosiduronic Acid; CBD-COOH-Gluc; Cannabidiol metabolite 1
EINECS	Contact for details

Quality Control

Our Cannabidiol β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 5.0 %
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.