Description

(5S)-4,5-Epoxy-5-Hydroxy-6α,21-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel bioactive molecules, particularly within the fields of neuroscience and medicinal chemistry. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on alkaloid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex indole alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control, method development, and identification in pharmaceutical and phytochemical analysis.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies aimed at discovering new therapeutic agents targeting neurological pathways.
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex natural products belonging to the akuammilan or related alkaloid families.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study interactions with specific enzymes or receptors.

Basic Information

Product Name	(5S)-4,5-Epoxy-5-Hydroxy-6α,21-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester
CAS No.	63950-46-9
Molecular Formula	C21H24N2O4
Molecular Weight	368.43 g/mol
Synonyms	Methyl (5S)-4,5-epoxy-5-hydroxy-6α,21-cyclo-4,5-secoakuammilan-17-oate; 6α,21-Cyclo-4,5-secoakuammilan-17-oic acid, 4,5-epoxy-5-hydroxy-, methyl ester, (5S)-; Secoakuammilan alkaloid derivative; Akuammilan epoxy ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (5S)-4,5-Epoxy-5-Hydroxy-6α,21-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing all test results are provided to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.