Description

(2ξ)-1-Acetyl-4,5-Bis(Acetyloxy)-1,2-Dihydro-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is a complex, semi-synthetic indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical intermediate, offering a unique structural framework for the development of novel bioactive molecules and complex natural product analogs. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of neurological and anti-cancer research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel indole alkaloid-based drug candidates for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore new pharmacophores and optimize biological activity.
• Natural Product Synthesis: Acts as a critical intermediate in the total or semi-synthesis of complex akuammiline-type alkaloids and their analogs.
• Biochemical Tool Compound: Employed in biochemical assays to study specific enzyme interactions or receptor binding mechanisms related to its structural class.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in laboratories analyzing related alkaloids.
• Academic Research: Supports advanced organic chemistry studies, including methodology development for complex molecule construction and stereochemical control.

Basic Information

Product Name	(2ξ)-1-Acetyl-4,5-Bis(Acetyloxy)-1,2-Dihydro-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester
CAS No.	63944-68-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methyl (2ξ)-1-acetyl-4,5-bis(acetyloxy)-1,2-dihydro-6α,21α-cyclo-4,5-secoakuammilan-17-oate; 1-Acetyl-4,5-bis(acetyloxy)-1,2-dihydro-6α,21α-cyclo-4,5-secoakuammilan-17-oic acid methyl ester; Secoakuammilan derivative; Akuammiline alkaloid intermediate; 17-O-Methyl ester of 1-acetyl-4,5-diacetoxy-secoakuammilan; 63944-68-3; Cyclo-secoakuammilan methyl ester
EINECS	Contact for details

Quality Control

Our (2ξ)-1-Acetyl-4,5-Bis(Acetyloxy)-1,2-Dihydro-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider inert gas purging or storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.