Description

4-Hydroxy-5-(Hydroxyimino)-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative with significant potential in advanced organic synthesis and pharmaceutical research. This compound serves as a critical specialized intermediate for developing novel bioactive molecules, particularly in the exploration of central nervous system (CNS) agents and other therapeutic areas. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of novel indole-based therapeutic agents.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories analyzing complex alkaloids.
• Organic Synthesis: Employed in advanced multi-step synthetic routes to construct complex polycyclic frameworks found in natural products.
• Biochemical Research: Investigated for its potential interactions with biological targets and receptors in pharmacological studies.

Basic Information

Product Name	4-Hydroxy-5-(Hydroxyimino)-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester
CAS No.	63944-64-9
Molecular Formula	C21H26N2O4
Molecular Weight	370.45 g/mol
Synonyms	Methyl 4-hydroxy-5-(hydroxyimino)-6α,21α-cyclo-4,5-secoakuammilan-17-oate; 6α,21α-Cyclo-4,5-secoakuammilan-17-oic acid, 4-hydroxy-5-(hydroxyimino)-, methyl ester; Secoakuammilan-17-oic acid methyl ester derivative; Indole alkaloid intermediate AKU-001; 17-Methyl carboxylate akuammilan derivative; 4,5-Secoakuammilan oxime methyl ester
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-5-(Hydroxyimino)-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and batch-to-batch consistency suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere to prevent oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.