Description

4,5-Dihydroxy-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is a highly specialized, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical building block, offering a unique, functionalized seco-akuammilan scaffold for developing novel bioactive molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who are engaged in the synthesis of complex natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of novel therapeutic agents, particularly those targeting neurological or other specialized biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or advanced starting material for structure-activity relationship (SAR) studies and lead optimization programs.
• Natural Product Synthesis: Acts as a critical intermediate in the total or semi-synthesis of complex indole alkaloids and their synthetic derivatives.
• Biochemical Research: Employed as a reference standard or probe compound in biochemical assays to study enzyme interactions or receptor binding.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of high-value, complex organic molecules for various advanced material or specialty chemical applications.

Basic Information

Product Name	4,5-Dihydroxy-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester
CAS No.	63944-63-8
Molecular Formula	C22H28N2O5
Molecular Weight	400.47 g/mol
Synonyms	Methyl 4,5-dihydroxy-6α,21α-cyclo-4,5-secoakuammilan-17-oate; 17-Carbonethoxy-4,5-dihydroxy-6α,21α-cyclo-4,5-secoakuammilan; Secoakuammilan-17-oic acid methyl ester derivative; 6α,21α-Cyclo-4,5-secoakuammilan-17-oic acid, 4,5-dihydroxy-, methyl ester; Akuammilan alkaloid derivative
EINECS	Contact for details

Quality Control

Our 4,5-Dihydroxy-6α,21α-Cyclo-4,5-Secoakuammilan-17-Oic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectral data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability if specified. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.