Description

Harmaline Hydrochloride Dihydrate is a high-purity alkaloid salt, specifically the hydrochloride salt of harmaline isolated as a dihydrate. This compound is of significant interest in biochemical and pharmacological research due to its role as a reference standard and active agent. It is primarily utilized by research institutions, pharmaceutical development labs, and analytical laboratories for method development and investigative studies.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of harmaline and related compounds in quality control laboratories.
• Biochemical Research: Serves as a key reagent and inhibitor in enzymatic studies, particularly for investigating monoamine oxidase (MAO) activity.
• Neuroscience Studies: Employed in preclinical research to study neurotransmitter systems and neuropharmacological effects.
• Analytical Chemistry: Functions as a certified reference material (CRM) for calibrating instruments and validating analytical methods like HPLC and LC-MS.
• Organic Synthesis: Acts as a crucial intermediate or starting material for the synthesis of more complex alkaloid derivatives and novel chemical entities.

Basic Information

Product Name	Harmaline Hydrochloride Dihydrate
CAS No.	63885-08-5
Molecular Formula	C13H14N2O · HCl · 2H2O
Molecular Weight	294.74 g/mol
Synonyms	Harmaline HCl Dihydrate; 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole hydrochloride dihydrate; 3,4-Dihydroharmine hydrochloride dihydrate; Dihydroharmine hydrochloride dihydrate; 7-Methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole hydrochloride dihydrate; Harmidine hydrochloride dihydrate; Telepathine hydrochloride dihydrate
EINECS	Contact for details

Quality Control

Our Harmaline Hydrochloride Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of residual solvents and moisture content. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	10.0% - 13.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.