Description

(7R,13As)-5,8,13,13A-Tetrahydro-2,9-Dihydroxy-3,10-Dimethoxy-7-Methyl-6H-Dibenzo[A,G]Quinolizinium CAS NO 63527-13-9 is a complex, naturally derived benzylisoquinoline alkaloid with a specific stereochemical configuration. This compound is of significant interest as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis and study of bioactive molecules, particularly those targeting neurological or cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Natural Product Chemistry: Acts as a model compound for the synthesis and structural analysis of related benzylisoquinoline alkaloids.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, calibration, and quality control of related substances.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, medicinal chemistry, and chemical biology.

Basic Information

Product Name	(7R,13As)-5,8,13,13A-Tetrahydro-2,9-Dihydroxy-3,10-Dimethoxy-7-Methyl-6H-Dibenzo[A,G]Quinolizinium
CAS No.	63527-13-9
Molecular Formula	C20H23NO4+
Molecular Weight	341.40 g/mol
Synonyms	7-Methylcorynoxan-17-ol, 16,17-Dihydro-16-hydroxy-17-methoxy-; Corynoxan-17-ol, 7-methyl-, 16,17-dihydro-16-hydroxy-17-methoxy-; (7R,13aR)-5,8,13,13a-Tetrahydro-2,9-dihydroxy-3,10-dimethoxy-7-methyl-6H-dibenzo[a,g]quinolizinium; Berbamine derivative; Isoquinolinium alkaloid
EINECS	Contact for details

Quality Control

Our production of this high-purity alkaloid adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.