Description

2,3-Dinor Thromboxane B2 is a stable metabolite of the potent pro-thrombotic and vasoconstrictive eicosanoid, Thromboxane A2. This compound is of significant value as a key biomarker for in vivo platelet activation and thromboxane biosynthesis in clinical and pharmacological research. It is primarily needed by pharmaceutical R&D laboratories, clinical diagnostics developers, and academic institutions focused on cardiovascular disease, inflammation, and thrombosis studies.

Application

• Biomarker Research: Used as a reference standard for the quantitative analysis of thromboxane metabolite levels in biological fluids (e.g., urine, plasma) to assess platelet function.
• Cardiovascular & Thrombosis Studies: Critical for investigating the role of thromboxane in heart disease, stroke, and other thrombotic disorders.
• Pharmacological Development: Serves as a key analyte in the development and efficacy testing of antiplatelet drugs such as aspirin and COX inhibitors.
• Clinical Diagnostics: Employed in the calibration and validation of immunoassays (ELISA, RIA) and LC-MS/MS methods for precise clinical measurement.
• Inflammation & Oxidative Stress Research: Used in studies exploring the link between eicosanoid pathways, inflammation, and oxidative stress.
• Metabolomics & Biochemical Pathway Analysis: An essential component in mapping arachidonic acid metabolism and eicosanoid profiling.

Basic Information

Product Name	2,3-Dinor Thromboxane B2
CAS No.	63250-09-9
Molecular Formula	C18H30O6
Molecular Weight	342.43 g/mol
Synonyms	2,3-Dinor TXB2; Dinor Thromboxane B2; 11-Dehydro-2,3-dinor-thromboxane B2; 9,12-Dihydroxy-8,10-heptadecadienoic acid; 9α,11,15-Trihydroxy-thromboxa-5,13-dien-1-oic acid (2,3-dinor); TXB2 Metabolite; Thromboxane B2 Metabolite II
EINECS	Contact for details

Quality Control

Our 2,3-Dinor Thromboxane B2 is produced and handled under strict quality protocols to ensure the high purity and consistency required for sensitive analytical applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and chromatographic data is provided to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is light-sensitive and easily oxidized; allow it to reach room temperature in a desiccator before opening to minimize moisture uptake and oxidative degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.