Description

Ribavirin 5'-Triphosphate is the active triphosphate metabolite of the broad-spectrum antiviral nucleoside ribavirin. This compound matters as a critical biochemical tool for studying viral RNA polymerase inhibition mechanisms and nucleotide metabolism. It is essential for researchers and manufacturers in pharmaceutical development, virology research, and diagnostic assay production, particularly for RNA viruses.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies of viral RNA-dependent RNA polymerases (RdRps).
• Antiviral Mechanism Studies: Critical for in vitro assays to elucidate the chain termination and mutagenic mechanisms of ribavirin's action.
• Pharmaceutical Reference Standard: Serves as a high-purity reference compound in the quality control and development of antiviral therapeutics.
• Diagnostic Kit Development: Employed in the formulation of kits for screening and studying antiviral drug efficacy.
• Nucleotide Metabolism Research: A key reagent for investigating intracellular nucleotide pool dynamics and enzyme kinetics.

Basic Information

Product Name	Ribavirin 5'-Triphosphate
CAS No.	63142-71-2
Molecular Formula	C8H15N4O14P3
Molecular Weight	508.14 g/mol
Synonyms	Ribavirin-TP; 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide 5'-triphosphate; Ribavirin triphosphate; RTF; Virazole 5'-triphosphate; 1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide 5'-triphosphate; RTP
EINECS	Contact for details

Quality Control

Our Ribavirin 5'-Triphosphate is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.