Description

(5β,12S,19β)-2,3-Didehydro-7β-Hydroxy-8β-Methyl-8A-Homo-20,21-Dinoraspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate and a valuable scaffold in organic synthesis. Its intricate structure makes it an essential building block for the research and development of novel bioactive compounds, particularly in the field of medicinal chemistry. This compound is primarily targeted towards pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the synthesis of complex natural product analogs and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel alkaloid-based drug candidates targeting neurological and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses due to its reactive functional groups and defined stereocenters.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with biological targets and potential enzyme inhibitory activity.
• Academic & Institutional Research: Utilized in advanced organic chemistry and natural product synthesis projects.

Basic Information

Product Name	(5β,12S,19β)-2,3-Didehydro-7β-Hydroxy-8β-Methyl-8A-Homo-20,21-Dinoraspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	62861-08-9
Molecular Formula	C22H28N2O3
Molecular Weight	368.47 g/mol
Synonyms	Methyl (5beta,12S,19beta)-2,3-didehydro-7beta-hydroxy-8beta-methyl-8a-homo-20,21-dinoraspidospermidine-3-carboxylate; 8a-Homoaspidospermidine-3-carboxylic acid, 2,3-didehydro-7-hydroxy-8-methyl-, methyl ester, (5beta,12S,19beta)-; Dinoraspidospermidine derivative; Aspidosperma alkaloid intermediate.
EINECS	Contact for details

Quality Control

Our (5β,12S,19β)-2,3-Didehydro-7β-Hydroxy-8β-Methyl-8A-Homo-20,21-Dinoraspidospermidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. While not certified to pharmacopeial standards unless specified, our standard production adheres to principles of current Good Manufacturing Practice (cGMP) for fine chemicals. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.