Description

1-(1-Ethoxyethyl)-5-Fluorouracil is a fluorinated pyrimidine derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound matters for its role in developing targeted chemotherapeutic agents, offering a pathway to more effective and selective cancer treatments. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on oncology drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluorouracil prodrugs and anti-cancer agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate new mechanisms of action for cancer cell inhibition.
• Prodrug Development: Serves as a precursor for designing compounds with improved bioavailability and targeted delivery profiles.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value fluorinated molecules.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry projects and method development.

Basic Information

Product Name	1-(1-Ethoxyethyl)-5-Fluorouracil
CAS No.	62679-91-8
Molecular Formula	C9H13FN2O3
Molecular Weight	216.21 g/mol
Synonyms	5-Fluoro-1-(1-ethoxyethyl)uracil; 1-(1-Ethoxyethyl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluorouracil, 1-(1-ethoxyethyl) derivative; EE-5-FU; 1-(α-Ethoxyethyl)-5-fluorouracil; NSC 379780; 5-FU 1-(1-ethoxyethyl) ether
EINECS	Contact for details

Quality Control

Our 1-(1-Ethoxyethyl)-5-Fluorouracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.