Description

Trimethylamine N-Oxide Dihydrate is a versatile organic osmolyte and methylamine derivative. This high-purity compound is critical for applications requiring precise control of protein stability and cellular osmoregulation. It serves as an essential reagent for biopharmaceutical research, diagnostic manufacturing, and advanced material science.

Application

• Protein Stabilization & Refolding: Used as a stabilizing agent and chemical chaperone in biotherapeutic formulation and protein purification processes.
• Diagnostic Reagents: A key component in the manufacturing of enzymatic assay kits and clinical diagnostic reagents.
• Osmolyte Research: Employed in molecular biology and cell culture studies to investigate cellular stress response and osmoregulation mechanisms.
• Pharmaceutical Intermediates: Serves as a building block and catalyst in the synthesis of specialized active pharmaceutical ingredients (APIs).
• Cosmetic & Personal Care: Functions as a humectant and moisturizing agent in high-end skincare formulations.
• Chemical Synthesis: Acts as a mild oxidant and solvent in various organic synthesis applications.

Basic Information

Product Name	Trimethylamine N-Oxide Dihydrate
CAS No.	62637-93-8
Molecular Formula	C₃H₉NO·2H₂O
Molecular Weight	111.14 g/mol (Anhydrous basis)
Synonyms	Trimethylamine Oxide Dihydrate; TMAO Dihydrate; TMANO Dihydrate; N,N-Dimethylmethanamine N-Oxide Dihydrate; (CH3)3NO·2H2O; Me3NO·2H2O; Oxotrimethylammonium Dihydrate
EINECS	Contact for details

Quality Control

Our Trimethylamine N-Oxide Dihydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling, to ensure it meets the stringent requirements of research and industrial applications. Certificates of Analysis (COA) detailing purity, water content, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent absorption of atmospheric moisture, which can affect purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	24.0% - 26.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
pH (5% solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.