Description

19-Hydroxy-10(S),19-Dihydrovitamin D3 is a key intermediate and reference standard in the synthesis and analytical research of vitamin D analogs. This compound matters for its critical role in the study of vitamin D metabolism and the development of novel therapeutic agents targeting related pathways. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on endocrinology, bone health, and cancer research.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of advanced vitamin D metabolites and novel calcitriol analogs for therapeutic applications.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (QC) of related vitamin D compounds via HPLC, LC-MS, or NMR.
• Biochemical Research: Employed in metabolic pathway studies to investigate the enzymatic conversion steps involving vitamin D hydroxylases.
• Drug Discovery: Serves as a precursor or a molecular scaffold in medicinal chemistry programs targeting vitamin D receptor (VDR) modulators.
• Academic Studies: Utilized in university and institutional research to explore the physiological roles and signaling mechanisms of vitamin D derivatives.

Basic Information

Product Name	19-Hydroxy-10(S),19-Dihydrovitamin D3
CAS No.	62077-06-9
Molecular Formula	C₂₇H₄₄O₂
Molecular Weight	400.64 g/mol
Synonyms	19-Hydroxy-10,19-dihydrovitamin D3; 19-Hydroxy-10(S),19-dihydroxycholecalciferol; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,19-triol (10S isomer); 19-Hydroxy-10,19-dihydroxycholecalciferol; 19-Hydroxy-10,19-dihydroxyvitamin D3; 19-OH-10,19-Dihydrovitamin D3; Vitamin D3 metabolite intermediate
EINECS	Contact for details

Quality Control

Our 19-Hydroxy-10(S),19-Dihydrovitamin D3 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term storage, keep the material in a freezer at -20°C or below. The container should be kept in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.