Description

(R)-2,3-Dihydro-3-Hydroxy-6-(2-Hydroxyethyl)-7-Hydroxymethyl-2,2,5-Trimethyl-1H-Inden-1-One is a high-purity chiral indanone derivative, a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). Its defined stereochemistry and functional group array make it a valuable building block for creating molecules with specific biological activity. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandin analogs and other potent bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct complex, stereodefined structures.
• Medicinal Chemistry Research: Serves as a core scaffold for the development and optimization of new chemical entities in drug discovery programs.
• Process Chemistry & Scale-up: Employed in the development of robust, scalable synthetic routes for GMP-grade API manufacturing.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(R)-2,3-Dihydro-3-Hydroxy-6-(2-Hydroxyethyl)-7-Hydroxymethyl-2,2,5-Trimethyl-1H-Inden-1-One
CAS No.	62043-46-3
Molecular Formula	C15H22O4
Molecular Weight	266.33 g/mol
Synonyms	(R)-3-Hydroxy-6-(2-hydroxyethyl)-7-(hydroxymethyl)-2,2,5-trimethyl-2,3-dihydro-1H-inden-1-one; (R)-2,3-Dihydro-3-hydroxy-6-(2-hydroxyethyl)-7-(hydroxymethyl)-2,2,5-trimethyl-1H-inden-1-one; (3R)-3-Hydroxy-6-(2-hydroxyethyl)-7-(hydroxymethyl)-2,2,5-trimethylindan-1-one; (R)-Indanone derivative; CAS 62043-46-3
EINECS	Contact for details

Quality Control

Every batch of our (R)-2,3-Dihydro-3-Hydroxy-6-(2-Hydroxyethyl)-7-Hydroxymethyl-2,2,5-Trimethyl-1H-Inden-1-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) confirming identity, purity (typically >97% by HPLC), chiral purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.