Description

H-Aaf-Amc, Tfa is a specialized protected amino acid derivative, specifically N-(9-Fluorenylmethoxycarbonyl)-3-(2-naphthyl)-L-alanine with a trifluoroacetyl protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of a unique aromatic side chain. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, sequence-specific peptides for drug discovery, development, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid for the automated synthesis of complex peptides.
• Pharmaceutical Research: Used in the development of peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a precursor for creating peptide tags and probes used in diagnostic assays and imaging.
• Material Science: Incorporation into bio-inspired polymers and surfaces to modify physicochemical properties.
• Academic & Contract Research: Fundamental reagent for studying protein-protein interactions and structure-activity relationships (SAR).

Basic Information

Product Name	H-Aaf-Amc, Tfa
CAS No.	62037-42-7
Molecular Formula	C₂₈H₂₂F₃NO₅
Molecular Weight	509.48 g/mol
Synonyms	Fmoc-3-(2-Naphthyl)-L-alanine; Fmoc-3-(2-Naphthyl)alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(naphthalen-2-yl)-L-alanine; Fmoc-2-Nal-OH; Fmoc-3-(2-Naphthyl)alanine; Nα-Fmoc-3-(2-naphthyl)-L-alanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(naphthalen-2-yl)propanoic acid
EINECS	Contact for details

Quality Control

Every batch of H-Aaf-Amc, Tfa is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), chiral purity, and identity is supplied with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.