Description

Disialoganglioside GD3 is a specific glycosphingolipid belonging to the ganglioside family, characterized by its two sialic acid residues. This compound is of significant interest in biochemical and biomedical research due to its role as a key antigen and signaling molecule in cellular processes. It is primarily utilized by research institutions and pharmaceutical developers focusing on immunology, oncology, and neuroscience for applications such as antibody production, cell marker studies, and the investigation of apoptosis and metastasis.

Application

• Biomedical Research: Used as a standard or antigen in studies related to cell surface markers, immune response, and cancer biology.
• Antibody Development: Serves as a critical hapten or immunogen for the production of monoclonal and polyclonal antibodies targeting GD3-expressing cells.
• Oncology Studies: Employed in research on melanoma, glioblastoma, and other cancers where GD3 is overexpressed, to study tumor progression and potential therapeutic targets.
• Neuroscience Research: Investigated for its role in neural development, cell differentiation, and neurodegenerative conditions.
• Diagnostic Reagent Formulation: A component in the development of diagnostic kits and assays for detecting specific cell types or disease states.
• Cell Signaling Pathways: Used to elucidate mechanisms of apoptosis, cell adhesion, and signal transduction mediated by gangliosides.

Basic Information

Item	Detail
Product Name	Disialoganglioside GD3
CAS No.	62010-37-1
Molecular Formula	C73H129N3O31
Molecular Weight	1568.8 g/mol
Synonyms	Ganglioside GD3; II3(NeuAc)2-LacCer; GD3 Ganglioside; Disialosylganglioside GD3; NeuAcα2-8NeuAcα2-3Galβ1-4Glcβ1-1'Cer; DGD3; 2,8-Disialosylganglioside; Lactosylceramide with two sialic acids
EINECS	Contact for details

Quality Control

Our Disialoganglioside GD3 is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques, including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material under an inert atmosphere or desiccated to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in chloroform/methanol mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.