Description

(-)-Vincovaline is a high-purity, naturally derived indole alkaloid of significant interest in advanced pharmaceutical research and development. This compound is valued for its specific stereochemistry and serves as a critical intermediate or reference standard in the synthesis and study of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology, neurology, and medicinal chemistry programs. Our supply ensures consistent quality and reliable availability for your most demanding projects.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control, method validation, and regulatory submissions in drug development.
• Medicinal Chemistry Research: Serves as a key chiral building block or precursor in the synthesis of novel therapeutic agents and analogs.
• Biological Activity Screening: Employed in in vitro and in vivo studies to investigate potential pharmacological properties and mechanisms of action.
• Academic Research: Utilized in university and institutional labs for studies in natural product chemistry, alkaloid biosynthesis, and chemical biology.
• Process Development: Acts as an intermediate in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(-)-Vincovaline
CAS No.	61949-65-3
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Vincovaline; (15S,19S)-19-Ethyl-19-hydroxy-15-(methoxycarbonyl)-1-methyl-16,17-didehydro-15,19-secocorynan-17-oic acid methyl ester; 15,19-Secocorynan-17-oic acid, 19-ethyl-19-hydroxy-15-(methoxycarbonyl)-1-methyl-16,17-didehydro-, methyl ester, (15S,19S)-; Methyl (15S,19S)-19-ethyl-19-hydroxy-15-(methoxycarbonyl)-1-methyl-16,17-didehydro-15,19-secocorynan-17-oate
EINECS	Contact for details

Quality Control

Our (-)-Vincovaline is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.