Description

1,2-Di11-cis-Eicosenoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid belonging to the phosphatidylcholine class, specifically a diacyl phospholipid with defined 11-cis-eicosenoyl fatty acid chains. This compound is critical for advanced research and development in lipid-based delivery systems, where precise molecular structure and purity are paramount for reproducible results. It is primarily utilized by pharmaceutical R&D teams, formulation scientists, and academic researchers working on liposomes, lipid nanoparticles (LNPs), and model membrane studies.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, uniform vesicles for drug delivery, particularly for nucleic acid (e.g., mRNA) encapsulation.
• Biomimetic Membrane Research: Used to construct defined model membranes (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and biophysical properties.
• Pharmaceutical Excipient Development: Serves as a critical raw material in the development of advanced parenteral and topical formulations requiring specific lipid components.
• Cell Culture & Biochemistry: Employed as a supplement in specialized cell culture media or as a substrate in enzymatic studies involving phospholipases.
• Analytical Reference Standard: Used as a high-purity standard in analytical methods such as HPLC and LC-MS for the identification and quantification of phospholipids in complex mixtures.
• Cosmetic Actives Delivery: Incorporated into high-end cosmetic formulations to enhance the skin delivery and stability of active ingredients.

Basic Information

Product Name	1,2-Di11-cis-Eicosenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	61596-54-1
Molecular Formula	C48H92NO8P
Molecular Weight	842.22 g/mol
Synonyms	1,2-Di(11Z-eicosenoyl)-sn-glycero-3-phosphocholine; PC(20:1(11Z)/20:1(11Z)); Dielaidoylphosphatidylcholine (isomer specific); 1,2-Di-(cis-11-Eicosenoyl)-L-α-Phosphatidylcholine; 20:1 PC; 1,2-Di(11Z-Eicosenoyl)-PC; DOEPC (specific isomer); Phosphatidylcholine (20:1/20:1)
EINECS	Contact for details

Quality Control

Our 1,2-Di11-cis-Eicosenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality systems suitable for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity, isomeric purity, and chemical purity. Certificates of Analysis (COA) with full analytical data are provided to ensure traceability and batch-to-batch consistency, supporting your critical formulation work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isomeric Purity (Fatty Acid Profile)	≥ 90% 11-cis isomer
Water Content (KF)	≤ 2.0 %
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.