Description

Phorboldibutyrate CAS NO 61557-88-8 is a specialized organic compound belonging to the phorbol ester family, valued for its role as a potent biochemical tool in research. This compound is critical for studying protein kinase C (PKC) activation pathways and related cellular signaling mechanisms. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for investigative and developmental applications.

Application

• Biochemical Research: As a potent activator of Protein Kinase C (PKC) isoforms for studying signal transduction, cell proliferation, and differentiation.
• Pharmacological Studies: Used in vitro to investigate the effects of PKC modulation on various disease models, including cancer and inflammatory conditions.
• Cell Biology: A key reagent for inducing specific cellular responses and studying downstream effects in controlled laboratory environments.
• Drug Discovery & Development: Serves as a reference standard and a tool compound for screening and validating potential therapeutic agents targeting the PKC pathway.
• Academic Research: Employed in university and institutional labs for fundamental research into molecular biology and enzymology.

Basic Information

Product Name	Phorboldibutyrate
CAS No.	61557-88-8
Molecular Formula	C28H38O8
Molecular Weight	502.60 g/mol
Synonyms	12-O-Tetradecanoylphorbol-13-butyrate; PDBu; Phorbol 12,13-Dibutyrate; 4α-Phorbol 12,13-Dibutyrate; TPA analogue; NSC 296962; Phorbol-12,13-dibutyrate; 12-O-Tetradecanoylphorbol 13-butyrate
EINECS	Contact for details

Quality Control

Our Phorboldibutyrate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.