Description

Trehalose 6,6'-Dimycolate is a high-purity, synthetic glycolipid derivative of trehalose, a non-reducing disaccharide. This compound is of significant interest in immunological research and pharmaceutical development due to its structural role as a key component of the mycobacterial cell wall, known as cord factor. It is primarily utilized by research institutions, diagnostic developers, and biopharmaceutical companies engaged in vaccine adjuvant research, immunology studies, and the development of novel therapeutic agents targeting mycobacterial infections.

Application

• Immunological Research: As a model antigen and immunomodulator for studying host-pathogen interactions, particularly with Mycobacterium tuberculosis.
• Vaccine Adjuvant Development: Investigated for its potent ability to stimulate both innate and adaptive immune responses in next-generation vaccine formulations.
• Diagnostic Reagent Manufacturing: Used in the production of high-specificity reagents for serological assays and tuberculosis (TB) diagnostic tests.
• Cell Biology Studies: Employed to investigate macrophage activation, granuloma formation, and other cellular responses to mycobacterial infection.
• Pharmaceutical Intermediates: Serves as a critical intermediate or reference standard in the synthesis and quality control of novel anti-tubercular drugs.
• Biochemical Standard: Acts as a purified standard for analytical methods such as HPLC, LC-MS, and NMR in quality control and research laboratories.

Basic Information

Product Name	Trehalose 6,6'-Dimycolate
CAS No.	61512-20-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cord Factor; Trehalose Dimycolate; TDM; α,α-Trehalose 6,6'-Dimycolate; 6,6'-Di-O-mycolyl-α,α-D-trehalose; Mycobacterial Cord Factor; Trehalose-6,6'-Dibehenate (common synthetic analog); 2,3,4,2',3',4'-Hexa-O-acetyl-6,6'-di-O-mycolyl-α,α-trehalose
EINECS	Contact for details

Quality Control

Our Trehalose 6,6'-Dimycolate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing results from NMR, HPLC, and other relevant tests are provided to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.