Description

N(6)-(2,2,6,6-Tetramethyl-1-Oxypiperidin-4-Yl)Adenine is a specialized adenine derivative functionalized with a TEMPO (2,2,6,6-tetramethylpiperidin-1-oxyl) radical moiety, offering unique chemical and biological properties. This compound is valued for its dual role as a biochemical probe and a precursor in advanced material synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, life sciences, and specialty chemical industries for applications ranging from radical chemistry studies to the development of novel therapeutic agents.

Application

• Biochemical Research: Acts as a spin-labeled nucleobase analog for Electron Paramagnetic Resonance (EPR) spectroscopy studies of nucleic acid structure, dynamics, and protein interactions.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting enzymes involved in nucleotide metabolism.
• Antioxidant Studies: Utilized as a model compound to investigate the biological activity and mechanisms of nitroxide radical-based antioxidants.
• Polymer Science: Employed as a functional monomer or initiator in controlled radical polymerization processes to create polymers with specific chain-end functionalities.
• Diagnostic Agent Development: Investigated for potential use in the development of contrast agents or molecular probes for advanced imaging techniques.
• Enzyme Inhibition: Studied for its potential to inhibit specific kinases or other adenine-binding enzymes due to its modified adenine structure.

Basic Information

Product Name	N(6)-(2,2,6,6-Tetramethyl-1-Oxypiperidin-4-Yl)Adenine
CAS No.	61468-65-3
Molecular Formula	C15H23N7O
Molecular Weight	317.39 g/mol
Synonyms	4-(6-Amino-9H-purin-9-yl)-2,2,6,6-tetramethylpiperidine-1-oxyl; 4-(6-Aminopurin-9-yl)-2,2,6,6-tetramethylpiperidine-1-oxyl; TEMPO-Adenine; N6-(TEMPO-4-yl)adenine; Adenine-TEMPO conjugate; 9H-Purin-6-amine, 9-[4-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)]-; 4-(6-Aminopurin-9-yl)-2,2,6,6-tetramethylpiperidin-1-ol N-oxyl
EINECS	Contact for details

Quality Control

Our N(6)-(2,2,6,6-Tetramethyl-1-Oxypiperidin-4-Yl)Adenine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.