Description

8-Hydroxy-n-n-Propylnoraporphine is a synthetic aporphine alkaloid derivative of significant research interest. This compound matters as a key intermediate and reference standard in the development and study of novel pharmaceutical agents targeting neurological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in neuroscience, medicinal chemistry, and drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel dopaminergic and serotonergic receptor ligands for potential therapeutic applications.
• Neuroscience Studies: Used as a reference standard or tool compound in in vitro and in vivo studies to investigate receptor binding affinity, signal transduction, and behavioral pharmacology.
• Medicinal Chemistry: Acts as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of aporphine-based molecules.
• Analytical Reference Standard: Employed in high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and nuclear magnetic resonance (NMR) for method development, validation, and quality control of related substances.
• Biochemical Assays: Utilized in competitive binding assays and functional screens to identify and characterize new compounds interacting with specific neurotransmitter receptors.

Basic Information

Product Name	8-Hydroxy-n-n-Propylnoraporphine
CAS No.	61367-89-3
Molecular Formula	C19H23NO2
Molecular Weight	297.39 g/mol
Synonyms	8-Hydroxy-N-n-propylnoraporphine; 8-OH-PNPA; 8-Hydroxy-N-propylnoraporphine; 11-Hydroxy-N-propylnoraporphine; (R)-8-Hydroxy-2-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[g]quinoline; N-Propyl-8-hydroxy-noraporphine; 8-Hydroxy-N-propylnoraporphin; Aporphine derivative 61367-89-3
EINECS	Contact for details

Quality Control

Our 8-Hydroxy-n-n-Propylnoraporphine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all test results against our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.