Description

1-Stearoyl-2-Arachidonoyl-Sn-Glycero-3-Pe is a high-purity, synthetic phospholipid, specifically a phosphatidylethanolamine (PE) species with defined acyl chains. This compound is critical for advanced research and development in lipidomics, membrane biophysics, and the formulation of complex lipid-based delivery systems. It is an essential reagent for scientists and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries who require precisely characterized lipids for model membrane studies, drug delivery vehicle development, and metabolic pathway analysis.

Application

• Biomedical Research: Used as a standard or substrate in lipidomics studies, enzyme assays (e.g., phospholipase A2), and investigations into cell signaling pathways involving arachidonic acid.
• Model Membrane Systems: A key component for constructing liposomes, supported lipid bilayers (SLBs), and other artificial membranes to study protein-lipid interactions and membrane dynamics.
• Drug Delivery: Serves as a functional excipient in the formulation of liposomal and lipid nanoparticle (LNP) carriers for targeted drug and gene delivery applications.
• Diagnostic Reagents: Employed in the development of diagnostic kits and assays that detect or quantify specific phospholipids or related enzymatic activities.
• Nutraceutical & Cosmetic R&D: Investigated for its potential bioactive properties in advanced skincare formulations and specialized nutritional supplements.

Basic Information

Product Name	1-Stearoyl-2-Arachidonoyl-Sn-Glycero-3-Pe
CAS No.	61216-62-4
Molecular Formula	C43H78NO8P
Molecular Weight	768.05 g/mol
Synonyms	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine; 18:0-20:4 PE; SAPE; PE(18:0/20:4(5Z,8Z,11Z,14Z)); 1-Octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine; Arachidonoyl Stearoyl Phosphatidylethanolamine; Phosphatidylethanolamine (18:0/20:4); L-α-Phosphatidylethanolamine, 1-stearoyl-2-arachidonoyl
EINECS	Contact for details

Quality Control

Every batch of our 1-Stearoyl-2-Arachidonoyl-Sn-Glycero-3-Pe is produced and analyzed under strict quality management protocols. We ensure identity, purity, and consistency through advanced analytical techniques including NMR, mass spectrometry, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, lipid profile, and solvent residues is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Once opened, purge the container with inert gas and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR & MS)	Conforms to structure
Assay (HPLC)	≥ 95% (Area %)
Purity (TLC)	Single major spot
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	< 1.0 %
Peroxide Value	< 2.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.