Description

Disodium (E)-1-Sulfonatodiazen-1-Ium-1,2-Diolate is a high-purity, water-soluble diazeniumdiolate compound, also known as a NONOate donor. This compound matters as a critical precursor for generating nitric oxide (NO) in controlled, research-grade applications, offering a reliable and consistent source for physiological and biochemical studies. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers focused on cardiovascular research, neurology, and signal transduction pathways.

Application

• Biochemical Research: As a nitric oxide (NO) donor for studying vasodilation, neurotransmission, and cellular signaling mechanisms.
• Pharmaceutical Development: A key intermediate in the synthesis of novel therapeutics targeting cardiovascular diseases and conditions involving NO pathways.
• Cell Culture Studies: Used to investigate the effects of nitric oxide on cell proliferation, apoptosis, and inflammatory responses under controlled conditions.
• Material Science: Potential application in the surface modification of biomaterials where localized NO release is desired to prevent platelet adhesion or bacterial biofilm formation.
• Analytical Standards: Serves as a certified reference material for calibrating instruments and validating analytical methods in pharmacokinetic and metabolic studies.

Basic Information

Product Name	Disodium (E)-1-Sulfonatodiazen-1-Ium-1,2-Diolate
CAS No.	61142-90-3
Molecular Formula	C2H4N3Na2O6S
Molecular Weight	259.11 g/mol
Synonyms	Disodium 1-Sulfonatodiazen-1-ium-1,2-diolate; Disodium NONOate; Disodium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate (common trade name context); Diazen-1-ium-1,2-diolate, 1-sulfo-, disodium salt; NOC-18 (a related diethylamine NONOate); Nitric Oxide Donor; 1-Sulfonatodiazen-1-ium-1,2-diolate disodium salt; (E)-Disodium 1-sulfonatodiazen-1-ium-1,2-diolate
EINECS	Contact for details

Quality Control

Our Disodium (E)-1-Sulfonatodiazen-1-Ium-1,2-Diolate is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and analytical standard production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Nitric Oxide Release	Confirmed by standard assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.