Description

Chiriquitoxin is a potent neurotoxin and sodium channel activator originally isolated from the skin of the Costa Rican frog *Atelopus chiriquiensis*. This compound is of significant interest in advanced pharmacological and neurological research due to its specific mechanism of action. It serves as a critical reference standard and research tool for scientists studying ion channel function, neurotoxicity, and the development of novel therapeutic agents or biosensors.

Application

• Neuroscience Research: Used as a selective tool compound to study voltage-gated sodium (NaV) channels and neuronal excitability.
• Pharmacological Reference Standard: Serves as a high-purity analytical standard for the identification and quantification of related toxins in research samples.
• Toxicology Studies: Employed in investigative toxicology to understand the effects of sodium channel activators and to develop potential antidotes.
• Drug Discovery & Development: Acts as a molecular probe in screening assays and structure-activity relationship (SAR) studies for new neuroactive compounds.
• Academic & Institutional Research: Essential for universities and research institutes conducting studies in neurobiology, electrophysiology, and natural product chemistry.

Basic Information

Product Name	Chiriquitoxin
CAS No.	61132-15-8
Molecular Formula	C17H25N5O8S2
Molecular Weight	491.54 g/mol
Synonyms	Chiriquitoxin; ATX II (historical, from *Anemonia sulcata* toxin II, often confused); Sodium Channel Toxin; Neurotoxin from *Atelopus chiriquiensis*; (2S,4S,5R,7R,8R,9S,10S,12S,13R,14S,15R,16R,18S)-15-[(2S)-2-Aminopropanamido]-8,14-dihydroxy-5,7,9,13,16-pentamethyl-2,10,12,18-tetraoxo-6,17-dioxa-3,11-dithia-1-azabicyclo[13.3.1]nonadecane-4-carboxylic acid (IUPAC); Chiriquitoxin-1
EINECS	Contact for details

Quality Control

Our Chiriquitoxin CAS NO 61132-15-8 is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and structural verification via mass spectrometry (MS) and nuclear magnetic resonance (NMR). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and batch-specific data is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.