Description

Acyl Coenzyme A Oxidase is a critical enzyme that catalyzes the first and rate-determining step in the peroxisomal β-oxidation of fatty acids. This makes it an essential biochemical tool for research into lipid metabolism, metabolic disorders, and peroxisomal function. It is primarily utilized by researchers and scientists in the fields of biochemistry, molecular biology, and pharmaceutical development. The product is supplied as a high-purity, lyophilized powder to ensure optimal activity and stability for demanding laboratory applications.

Application

• Biochemical Research: Fundamental studies on fatty acid β-oxidation pathways and peroxisomal biology.
• Enzyme Activity Assays: Used as a standard or reagent in spectrophotometric or fluorometric assays to measure enzymatic activity in biological samples.
• Diagnostic Kit Development: A key component in the development of in-vitro diagnostic (IVD) kits for detecting metabolic diseases related to peroxisomal dysfunction.
• Pharmaceutical Screening: Employed in drug discovery platforms to identify and evaluate potential modulators of lipid metabolism for treating conditions like obesity, diabetes, or X-linked adrenoleukodystrophy (X-ALD).
• Metabolic Pathway Analysis: Used in conjunction with other enzymes to reconstruct and study specific metabolic pathways in vitro.
• Academic & Industrial R&D: Essential for university laboratories, contract research organizations (CROs), and biotech companies conducting advanced life science research.

Basic Information

Product Name	Acyl Coenzyme A Oxidase
CAS No.	61116-22-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acyl-CoA Oxidase; Palmitoyl-CoA Oxidase; Fatty Acyl-CoA Oxidase; ACOX; EC 1.3.3.6; Acyl-Coenzyme A Oxidase; Straight-chain acyl-CoA oxidase
EINECS	Contact for details

Quality Control

Every batch of our Acyl Coenzyme A Oxidase is subjected to rigorous analytical testing to ensure high specific activity, purity, and lot-to-lot consistency suitable for research applications. Our quality commitment includes verification of identity and functional performance. A comprehensive Certificate of Analysis (COA) detailing purity, activity (U/mg), and stability data is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. After reconstitution, aliquot and store at -70°C to minimize activity loss. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms
Specific Activity	≥ [Value] U/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	Reported on COA
Solubility	Fully soluble in recommended buffer
Stability	Retains ≥ 90% activity after 12 months at -20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.