Description

Bis(3',5')-Cyclic Diguanylic Acid CAS NO 61093-23-0 is a high-purity, biologically significant cyclic dinucleotide that serves as a key secondary messenger in bacterial signaling pathways. This compound is essential for research and development in microbiology and pharmaceutical sciences, particularly in the study of bacterial biofilm formation and virulence. It is a critical reagent for academic institutions, biotechnology firms, and pharmaceutical companies engaged in antimicrobial research, enzymology studies, and the development of novel therapeutic agents targeting bacterial communication systems.

Application

• Biochemical Research: Fundamental studies on bacterial second messenger signaling, quorum sensing, and cyclic di-GMP metabolism.
• Pharmaceutical Development: As a reference standard and key intermediate in the R&D of novel antibiotics and anti-biofilm agents.
• Enzymology: Substrate for studying the activity of diguanylate cyclases (DGCs) and phosphodiesterases (PDEs) involved in cyclic di-GMP synthesis and degradation.
• Microbiology: Investigation of bacterial virulence, motility, and the transition between planktonic and sessile lifestyles.
• Diagnostic Reagent Manufacturing: Potential use in developing assays and kits for bacterial detection and characterization.
• Cell Signaling Studies: Tool compound for probing nucleotide-based signaling networks in prokaryotic systems.

Basic Information

Product Name	Bis(3',5')-Cyclic Diguanylic Acid
CAS No.	61093-23-0
Molecular Formula	C20H24N10O14P2
Molecular Weight	690.40 g/mol
Synonyms	Cyclic di-GMP; Bis(3',5')-cyclic diguanylate; c-di-GMP; Cyclic diguanylic acid; 3',5'-Cyclic diguanylic acid; Cyclic diguanosine monophosphate; Cyclic diguanosine 3',5'-monophosphate; Cyclic bis(3'→5') diguanylic acid
EINECS	Contact for details

Quality Control

Our Bis(3',5')-Cyclic Diguanylic Acid is produced and tested under stringent quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support research and development with material that meets the high standards required for reliable and reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated at the recommended temperature.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.