Description

(S)-(-)-Canadine Di-p-Toluoyl-D-Tartrate is a high-purity chiral chemical derivative of canadine, a tetrahydroprotoberberine alkaloid. This compound is a critical intermediate and reference standard in advanced pharmaceutical research and asymmetric synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly those targeting neurological pathways and requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex bioactive molecules and potential drug candidates.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate alkaloid biosynthesis and receptor interactions.
• Asymmetric Synthesis: Serves as a precursor or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Analytical Standard: Employed as a high-purity calibrant in chromatographic methods (HPLC, LC-MS) for quality control and method validation.
• Natural Product Chemistry: Used in the study and semi-synthesis of protoberberine and related isoquinoline alkaloids.

Basic Information

Product Name	(S)-(-)-Canadine Di-p-Toluoyl-D-Tartrate
CAS No.	61065-22-3
Molecular Formula	C38H35NO9
Molecular Weight	649.69 g/mol
Synonyms	(S)-Canadine Di-p-Toluoyl-D-Tartrate; (-)-Canadine Di-p-Toluoyl-D-Tartrate; (S)-(-)-Canadine Ditoluoyl-D-Tartrate; Canadine D-(-)-Di-p-Toluoyltartrate; (5S)-Canadine Di-p-Toluoyl-D-Tartrate; Tetrahydroberberine Di-p-Toluoyl-D-Tartrate; (13aS)-5,8,13,13a-Tetrahydro-3,10-dimethoxy-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-9-yl 2,3-bis(4-methylbenzoyloxy)butanedioate
EINECS	Contact for details

Quality Control

Our (S)-(-)-Canadine Di-p-Toluoyl-D-Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a desiccated environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.