Description

Fenoterol o-β-D-Glucuronide is a major, pharmacologically inactive metabolite of the β-2 adrenergic receptor agonist Fenoterol, formed via glucuronidation. This reference standard is critical for analytical and research applications, enabling precise quantification and metabolic profiling. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory bodies for method development, validation, and bioanalytical studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantitative analysis of Fenoterol and its metabolites in biological matrices (e.g., plasma, urine) using HPLC, LC-MS, or GC-MS.
• Metabolic Pathway Studies: Used in pharmacokinetic and ADME (Absorption, Distribution, Metabolism, Excretion) research to elucidate the metabolic fate of Fenoterol.
• Bioanalytical Method Development: Essential for developing and validating robust, sensitive, and specific analytical methods for clinical and preclinical studies.
• Quality Control in Manufacturing: Employed in the quality control of Fenoterol-based drug substances and products to monitor and control related substances.
• Doping Control Analysis: Acts as a key reference compound in anti-doping laboratories for the detection of β-2 agonist misuse in sports.
• Regulatory Compliance & Documentation: Supports regulatory submissions (e.g., to FDA, EMA) by providing definitive proof of identity and purity for metabolite characterization.

Basic Information

Product Name	Fenoterol o-β-D-Glucuronide
CAS No.	61046-78-4
Molecular Formula	C24H33NO11
Molecular Weight	511.52 g/mol
Synonyms	Fenoterol Glucuronide; Fenoterol 4'-O-β-D-Glucuronide; 1-(3,5-Dihydroxyphenyl)-2-{[4-(β-D-glucopyranuronosyloxy)-1-methyl-1H-imidazol-2-yl]methoxy}ethan-1-ol; Fenoterol O-Glucuronide; Fenoterol Metabolite; TH 1165a Glucuronide; o-Glucuronide Fenoterol
EINECS	Contact for details

Quality Control

Our Fenoterol o-β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets high-purity standards suitable for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.