Description

Suc-Ala-Ala-Ala-Ala-Ala-Pna CAS NO 61043-68-3 is a synthetic, chromogenic peptide substrate specifically designed for protease activity assays. This compound is of critical importance for biochemical research and pharmaceutical development, serving as a highly sensitive tool for the detection and quantification of enzyme activity. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in enzymology, drug discovery, and quality control processes.

Application

• Protease Enzyme Assays: Primary substrate for the kinetic study and activity measurement of various proteases, including elastase and subtilisin.
• Biochemical Research: Used in fundamental research to investigate enzyme mechanisms, inhibition kinetics, and substrate specificity.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential protease inhibitor drug candidates.
• Diagnostic Development: Integral component in the formulation of diagnostic kits for detecting protease-related physiological conditions or pathogenic enzyme activity.
• Quality Control in Biotechnology: Used to standardize and validate the activity of enzyme preparations in biomanufacturing.

Basic Information

Product Name	Suc-Ala-Ala-Ala-Ala-Ala-Pna
CAS No.	61043-68-3
Molecular Formula	C34H48N8O12
Molecular Weight	760.80 g/mol
Synonyms	N-Succinyl-Ala-Ala-Ala-Ala-Ala-p-nitroanilide; Suc-(Ala)5-pNA; Suc-AAAAA-pNA; N-Succinyl-pentaanilide p-nitroanilide; Protease Substrate V (Elastase Substrate); Suc-Ala5-NA; N-Succinyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide
EINECS	Contact for details

Quality Control

Our Suc-Ala-Ala-Ala-Ala-Ala-Pna is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by mass spectrometry (MS) and infrared spectroscopy (IR). Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.