Description

Succinyl-Alanyl-Alanine-4-Nitroanilide is a specialized chromogenic peptide substrate designed for enzymatic assays. This compound is critical for researchers and quality control laboratories requiring precise, reliable, and reproducible results in protease activity studies. It is primarily utilized in the pharmaceutical, biotechnology, and diagnostic sectors for enzyme kinetics, inhibitor screening, and biochemical research.

Application

• Protease Enzyme Assays: A key chromogenic substrate for quantifying the activity of various proteolytic enzymes, including elastase and related serine proteases.
• Pharmaceutical Research & Development: Used in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors for drug discovery.
• Biochemical Research: Essential for studying enzyme kinetics, mechanism of action, and substrate specificity in academic and industrial laboratories.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits and reagents for clinical testing and biomarker detection.
• Quality Control in Biologics: Employed to monitor and validate the purity and activity of enzyme-based biopharmaceutical products.

Basic Information

Product Name	Succinyl-Alanyl-Alanine-4-Nitroanilide
CAS No.	61043-66-1
Molecular Formula	C18H23N5O7
Molecular Weight	421.41 g/mol
Synonyms	Suc-Ala-Ala-pNA; Suc-AAP-pNA; N-Succinyl-Ala-Ala-p-nitroanilide; N-Succinyl-L-alanyl-L-alanine 4-nitroanilide; Suc-AA-pNA; Substrate for Elastase; Chromogenic Elastase Substrate; Suc-(Ala)2-pNA
EINECS	Contact for details

Quality Control

Our Succinyl-Alanyl-Alanine-4-Nitroanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and residual solvent analysis, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.