Description

Z-Ala-Ala-Pna is a specialized synthetic peptide substrate designed for enzymatic activity studies. This compound is a critical tool for researchers and manufacturers requiring precise biochemical analysis and process control. It is primarily utilized in the life sciences sector for investigating protease kinetics and developing high-throughput screening assays. The product is supplied to ensure consistent performance and reliable results in demanding laboratory and industrial environments.

Application

• Protease Enzyme Assays: Acts as a chromogenic substrate for the kinetic characterization and inhibition studies of various proteases, including elastase and related serine proteases.
• Biochemical Research: Used in academic and industrial R&D to study enzyme mechanisms, substrate specificity, and catalytic efficiency.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential therapeutic protease inhibitors.
• Diagnostic Reagent Development: Serves as a key component in the formulation of test kits and reagents for clinical and research diagnostics.
• Quality Control in Biomanufacturing: Applied in-process testing to monitor protease activity during the production of biologics and other protein-based products.

Basic Information

Product Name	Z-Ala-Ala-Pna
CAS No.	61043-58-1
Molecular Formula	C₂₀H₂₂N₄O₆
Molecular Weight	414.41 g/mol
Synonyms	Z-Ala-Ala-pNA; N-CBZ-Alanyl-Alanine 4-Nitroanilide; CBZ-Ala-Ala-pNA; Nα-Carbobenzoxy-L-alanyl-L-alanine 4-nitroanilide; Z-Ala-Ala-4-nitroanilide; Ala-Ala-pNA (Z-); N-Carbobenzyloxyalanylalanyl-p-nitroanilide; Substrate for Elastase
EINECS	Contact for details

Quality Control

Every batch of Z-Ala-Ala-Pna is subjected to rigorous analytical testing to ensure identity, purity, and performance consistency. Our quality system is designed to meet the stringent requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identification, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.