Description

2-Hexadecanoylthio-1-Ethylphosphorylcholine is a synthetic phospholipid derivative, specifically a thioester analog of a lysophosphatidylcholine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key intermediate or model compound in the study of lipid metabolism, membrane biophysics, and signal transduction pathways. It is primarily utilized by research institutions and development laboratories in the life sciences sector, particularly those focused on lipidomics, drug delivery systems, and the investigation of enzymatic processes involving phospholipases.

Application

• Biochemical Research: Serves as a critical substrate or inhibitor in enzymatic studies, particularly for phospholipase A2 (PLA2) and other lipase assays.
• Lipidomics & Metabolomics: Used as a standard or reference compound in mass spectrometry-based lipid profiling and metabolic pathway analysis.
• Pharmaceutical Development: Acts as a synthetic intermediate or a model compound for designing novel lipid-based drug delivery vehicles, such as liposomes and micelles.
• Membrane Biophysics: Employed in studies investigating the properties and dynamics of artificial lipid bilayers and membrane models.
• Cell Signaling Studies: Utilized to explore the role of lysophospholipid derivatives in cellular communication and inflammatory responses.
• Diagnostic Reagent Formulation: Potential component in the development of specialized diagnostic kits for enzyme activity detection.

Basic Information

Product Name	2-Hexadecanoylthio-1-Ethylphosphorylcholine
CAS No.	60793-01-3
Molecular Formula	C23H48NO5PS
Molecular Weight	481.66 g/mol
Synonyms	1-Hexadecanoylthio-2-ethylphosphorylcholine; Hexadecanoylthioethylphosphorylcholine; S-Hexadecanoyl-2-thioethylphosphorylcholine; 2-(Hexadecanoylthio)ethyl 2-(trimethylammonio)ethyl phosphate; Thio-PAF C-16; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine thioether analog; S-Palmitoyl-2-thioethylphosphorylcholine
EINECS	Contact for details

Quality Control

Our 2-Hexadecanoylthio-1-Ethylphosphorylcholine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.