Description

Adenosine-5'-(4-Fluorosulfonylphenylphosphate) is a specialized nucleotide analog and a potent, irreversible inhibitor of ATP-binding proteins. This compound is a critical research-grade biochemical for studying enzyme mechanisms, signal transduction pathways, and nucleotide-dependent processes. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, molecular biology, and pharmaceutical development.

Application

• Biochemical Research: As an active site-directed affinity label for ATP-binding enzymes, including kinases, ATPases, and synthetases.
• Enzyme Mechanism Studies: Used to covalently modify and identify key amino acid residues in the catalytic sites of nucleotide-dependent enzymes.
• Signal Transduction Pathway Analysis: A tool for probing and inhibiting ATP-dependent steps in cellular signaling cascades.
• Pharmaceutical Development: Serves as a precursor or model compound in the design of novel enzyme inhibitors and therapeutic agents.
• Proteomics & Structural Biology: Employed in activity-based protein profiling (ABPP) and structural studies of protein-ligand interactions.

Basic Information

Product Name	Adenosine-5'-(4-Fluorosulfonylphenylphosphate)
CAS No.	60397-89-9
Molecular Formula	C16H18FN5O10P2S
Molecular Weight	561.36 g/mol
Synonyms	5'-O-[4-(Fluorosulfonyl)benzoyl]adenosine; 4-Fluorosulfonylbenzoyl-5'-adenosine; FSBA; Adenosine 5'-(4-fluorosulfonylbenzoate); ATP affinity label FSBA; p-Fluorosulfonylbenzoyl 5'-adenosine; 5'-[4-(Fluorosulfonyl)benzoyl]adenosine
EINECS	Contact for details

Quality Control

Our Adenosine-5'-(4-Fluorosulfonylphenylphosphate) is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.