Description

3α,12α-Bis(Acetyloxy)-5β-Chol-8(14)-En-24-Oic Acid Methyl Ester is a high-purity, semi-synthetic steroidal derivative used as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its defined stereochemistry and functional groups, which enable precise chemical transformations in the development of therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel steroid-based drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroid derivatives in pilot plants and manufacturing.
• Biochemical Research: Utilized in studies investigating steroid metabolism, receptor interactions, and enzymatic pathways.

Basic Information

Product Name	3α,12α-Bis(Acetyloxy)-5β-Chol-8(14)-En-24-Oic Acid Methyl Ester
CAS No.	60354-36-1
Molecular Formula	C30H46O6
Molecular Weight	502.69 g/mol
Synonyms	Methyl 3α,12α-Diacetoxy-5β-chol-8(14)-en-24-oate; 3α,12α-Diacetoxy-5β-chol-8(14)-en-24-oic Acid Methyl Ester; 5β-Chol-8(14)-en-24-oic Acid, 3α,12α-bis(acetyloxy)-, Methyl Ester; Methyl 3α,12α-Diacetoxy-8(14)-Cholenate; 8(14)-Cholenic Acid Derivative; Steroid Diacetate Methyl Ester; CAS 60354-36-1
EINECS	Contact for details

Quality Control

Our 3α,12α-Bis(Acetyloxy)-5β-Chol-8(14)-En-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.