Description

Chondroitin C Lyase is a highly specific enzyme that catalyzes the eliminative cleavage of chondroitin sulfate C (dermatan sulfate) at β1,4-hexosaminidic linkages. This product is essential for the structural analysis and characterization of glycosaminoglycans (GAGs), providing critical insights into their composition and function. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications ranging from drug development to quality control of biopharmaceuticals.

Application

• Glycosaminoglycan (GAG) Analysis: Used in research laboratories for the specific depolymerization and sequencing of chondroitin sulfate C/dermatan sulfate chains.
• Biopharmaceutical Characterization: Critical for analyzing the structure of heparin-like contaminants or related GAGs in protein-based therapeutics to ensure product safety and efficacy.
• Diagnostic Reagent Production: Employed in the manufacture of enzymatic assay kits for the detection and quantification of specific GAGs in clinical samples.
• Biomaterial Research: Applied in studies investigating the role of extracellular matrix components in tissue engineering and regenerative medicine.
• Enzymatic Digestions: Used in conjunction with other lyases (e.g., chondroitin ABC lyase) for comprehensive GAG profiling and disaccharide analysis.
• Quality Control: Serves as a reference standard or active component in QC protocols for products derived from or containing GAGs.

Basic Information

Product Name	Chondroitin C Lyase
CAS No.	60184-91-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chondroitinase C; Chondroitin AC Lyase; Chondroitin Sulfate C Lyase; Chondroitin Sulfate AC Lyase; Chondroitin AC Eliminase; EC 4.2.2.-; Dermatan Sulfate Lyase
EINECS	Contact for details

Quality Control

Our Chondroitin C Lyase is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high specific activity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as activity, protein content, and absence of contaminating enzymatic activities. We adhere to relevant industry standards for research and diagnostic enzyme production.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content	By UV absorbance or Bradford assay
Contaminating Activities (Chondroitin ABC/B Lyase)	Not detected
Solubility	Fully soluble in recommended buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.