Description

Doxycycline CAS NO 60080-38-8 is a broad-spectrum, semi-synthetic tetracycline antibiotic. It is valued for its high potency, excellent bioavailability, and effectiveness against a wide range of gram-positive and gram-negative bacteria, as well as atypical pathogens. This makes it a critical active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical and veterinary medicine industries, where it is formulated into capsules, tablets, and injectables.

Application

• Human Pharmaceutical Formulations: Primary API for oral and injectable antibiotics treating respiratory tract infections, Lyme disease, acne, and malaria prophylaxis.
• Veterinary Medicine: Key ingredient in treatments for livestock, poultry, and companion animals for bacterial infections and disease control.
• Research & Development: Used as a biochemical tool in life science research, particularly in studies requiring tetracycline-regulated gene expression systems.
• Aquaculture: Employed in medicated feeds to control bacterial diseases in farmed fish and shrimp.
• Generic Drug Manufacturing: Sourced by generic pharmaceutical companies for producing cost-effective antibiotic therapies.

Basic Information

Item	Detail
Product Name	Doxycycline
CAS No.	60080-38-8
Molecular Formula	C₂₂H₂₄N₂O₈
Molecular Weight	444.43 g/mol
Synonyms	Doxycycline Hydate; Doxycycline Monohydrate; Vibramycin; Doxy 100; GS-3065; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate; α-6-Deoxy-5-oxytetracycline
EINECS	262-042-5

Quality Control

Our doxycycline is produced under strict quality management systems. Every batch is tested to meet or exceed relevant pharmacopeial standards, including USP, EP, and BP monographs. Rigorous in-process and final release testing ensures identity, purity, potency, and the control of specified impurities. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
Water Content (KF)	1.5% - 3.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%
Related Substances (HPLC)	Meets EP/USP requirements
Specific Optical Rotation	-105° to -120°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.