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n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine CAS NO 60037-60-7


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CAS No.:60037-60-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine is a highly pure, synthetic sphingolipid derivative, specifically a ceramide-1-phosphate analog with a very long-chain fatty acid (lignoceric acid, C24:0). This compound is a critical biochemical tool for advanced research into lipid signaling pathways, membrane biophysics, and cellular regulation. It is essential for scientists and product developers in pharmaceutical R&D, academic biochemistry, and advanced cosmetics research who require well-defined, high-purity lipid standards and bioactive intermediates.

Application

  • Biochemical Research: As a key standard and substrate for studying sphingolipid metabolism, ceramide-1-phosphate signaling pathways, and lipid-protein interactions.
  • Pharmaceutical Development: Used in the investigation of novel drug targets related to inflammation, apoptosis, and cell proliferation where ceramide-1-phosphate plays a regulatory role.
  • Lipidomics & Analytical Standards: Serves as a high-purity reference compound for mass spectrometry (LC-MS/MS) and chromatography (HPLC) to quantify and identify related lipids in complex biological samples.
  • Advanced Cosmetic Science: Investigated for its potential bioactive properties in skin barrier function and epidermal cell signaling for high-end skincare formulations.
  • Membrane Biophysics Studies: Utilized in model membrane systems (e.g., liposomes, lipid bilayers) to study the effects of specific ceramide species on membrane structure, fluidity, and domain formation.
  • Cell Culture & In Vitro Studies: Applied in cell-based assays to elucidate the specific biological functions of D-erythro-sphingosine-based lipids with very long-chain acyl groups.

Basic Information

Product Name n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine
CAS No. 60037-60-7
Molecular Formula C52H105N2O8P
Molecular Weight 917.38 g/mol
Synonyms N-Lignoceroylsphingosylphosphorylcholine; Ceramide-1-Phosphate (C24:0); N-(Tetracosanoyl)-D-erythro-sphingosylphosphorylcholine; Lignoceroyl Ceramide-1-Phosphate; C24:0 Cer-1-P; D-erythro-C24:0-Ceramide-1-phosphate; N-Lignoceroyl-D-erythro-sphingosine-1-phosphocholine; LCPC
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Quality Control

Our n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade biochemicals. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (Mass Spec) Conforms (M+H+ or M-H-)
Purity (HPLC) ≥ 95% (Area %)
Assay (HPLC) ≥ 98% (by weight)
Solubility Soluble in chloroform, methanol, DMSO
Loss on Drying ≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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