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n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine CAS NO 60037-60-7
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CAS No.:60037-60-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine is a highly pure, synthetic sphingolipid derivative, specifically a ceramide-1-phosphate analog with a very long-chain fatty acid (lignoceric acid, C24:0). This compound is a critical biochemical tool for advanced research into lipid signaling pathways, membrane biophysics, and cellular regulation. It is essential for scientists and product developers in pharmaceutical R&D, academic biochemistry, and advanced cosmetics research who require well-defined, high-purity lipid standards and bioactive intermediates.
Application
- Biochemical Research: As a key standard and substrate for studying sphingolipid metabolism, ceramide-1-phosphate signaling pathways, and lipid-protein interactions.
- Pharmaceutical Development: Used in the investigation of novel drug targets related to inflammation, apoptosis, and cell proliferation where ceramide-1-phosphate plays a regulatory role.
- Lipidomics & Analytical Standards: Serves as a high-purity reference compound for mass spectrometry (LC-MS/MS) and chromatography (HPLC) to quantify and identify related lipids in complex biological samples.
- Advanced Cosmetic Science: Investigated for its potential bioactive properties in skin barrier function and epidermal cell signaling for high-end skincare formulations.
- Membrane Biophysics Studies: Utilized in model membrane systems (e.g., liposomes, lipid bilayers) to study the effects of specific ceramide species on membrane structure, fluidity, and domain formation.
- Cell Culture & In Vitro Studies: Applied in cell-based assays to elucidate the specific biological functions of D-erythro-sphingosine-based lipids with very long-chain acyl groups.
Basic Information
| Product Name | n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine |
| CAS No. | 60037-60-7 |
| Molecular Formula | C52H105N2O8P |
| Molecular Weight | 917.38 g/mol |
| Synonyms | N-Lignoceroylsphingosylphosphorylcholine; Ceramide-1-Phosphate (C24:0); N-(Tetracosanoyl)-D-erythro-sphingosylphosphorylcholine; Lignoceroyl Ceramide-1-Phosphate; C24:0 Cer-1-P; D-erythro-C24:0-Ceramide-1-phosphate; N-Lignoceroyl-D-erythro-sphingosine-1-phosphocholine; LCPC |
| EINECS | Contact for details |
Quality Control
Our n-Lignoceroyl-D-Erythro-Sphingosylphosphorylcholine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade biochemicals. Certificates of Analysis (COA) are available upon request.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (Mass Spec) | Conforms (M+H+ or M-H-) |
| Purity (HPLC) | ≥ 95% (Area %) |
| Assay (HPLC) | ≥ 98% (by weight) |
| Solubility | Soluble in chloroform, methanol, DMSO |
| Loss on Drying | ≤ 2.0 % |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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