Description

Tris(Hydroxymethyl)Aminomethane Phosphate is a high-purity organic phosphate salt derived from the widely used biological buffer Tris. This compound is valued for its role as a buffering agent and a source of phosphate ions in critical biochemical and pharmaceutical processes. It is essential for researchers and manufacturers requiring precise pH control and ionic strength in sensitive formulations. Key industries that utilize this product include pharmaceutical development, molecular biology, and diagnostic reagent manufacturing.

Application

• Pharmaceutical Buffer: Used in the formulation of injectables, ophthalmic solutions, and other parenteral products where precise pH control is critical.
• Molecular Biology Reagent: Serves as a component in buffer systems for nucleic acid electrophoresis, protein purification, and enzyme assays.
• Diagnostic Kits: Employed as a stabilizing and buffering agent in the production of clinical diagnostic reagents and test strips.
• Cell Culture Media: Acts as a buffering agent to maintain physiological pH in various cell culture and fermentation applications.
• Biochemical Research: Provides a defined phosphate source and buffering capacity in a wide range of in vitro biochemical studies and experiments.

Basic Information

Product Name	Tris(Hydroxymethyl)Aminomethane Phosphate
CAS No.	6992-39-8
Molecular Formula	C4H14NO7P
Molecular Weight	219.13 g/mol
Synonyms	Tris Phosphate; Trometamol Phosphate; Tris(Hydroxymethyl)Aminomethane Dihydrogen Phosphate; 2-Amino-2-(hydroxymethyl)-1,3-propanediol Dihydrogen Phosphate; THAM Phosphate; Tromethamine Phosphate; TRIS Phosphate Buffer Salt; Tris Buffer Phosphate Salt
EINECS	230-274-6

Quality Control

Our Tris(Hydroxymethyl)Aminomethane Phosphate is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. The product can be supplied to meet various pharmacopeial standards (e.g., USP, EP) upon request, ensuring reliable performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0 %
pH (1% Solution)	Contact for details
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1 %
Chloride (Cl)	≤ 0.01 %
Sulfate (SO4)	≤ 0.01 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.