Description

Trizma Sulfate CAS NO 6992-38-7 is the sulfate salt of Tris(hydroxymethyl)aminomethane, a high-purity biochemical buffer agent essential for maintaining stable pH conditions in sensitive environments. Its primary value lies in providing superior buffering capacity and ionic strength control compared to the free base form. This product is critical for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic industries who require precise and reliable pH stabilization for enzymatic reactions, cell culture media, and electrophoresis.

Application

• Biochemical & Molecular Biology Research: As a key component in buffer systems for protein purification, nucleic acid electrophoresis (e.g., TAE, TBE buffers), and enzyme activity assays.
• Pharmaceutical Formulation: Used as an excipient or buffering agent in the development and manufacturing of injectable drugs, vaccines, and diagnostic reagents to control pH and ensure stability.
• Cell Culture & Microbiology: Employed in the preparation of culture media and balanced salt solutions to maintain physiological pH for cell growth and viability studies.
• Diagnostic Kits: A vital ingredient in buffers for clinical diagnostic assays, including ELISA and various chromatography applications, ensuring consistent and accurate test results.
• Industrial Biotechnology: Utilized in fermentation processes and downstream purification steps in bioprocessing to optimize yield and maintain product integrity.

Basic Information

Product Name	Trizma Sulfate
CAS No.	6992-38-7
Molecular Formula	C4H11NO3 · H2SO4
Molecular Weight	221.20 g/mol
Synonyms	Tris Sulfate; Trometamol Sulfate; Tris(Hydroxymethyl)Aminomethane Sulfate; 2-Amino-2-(hydroxymethyl)-1,3-propanediol Sulfate; THAM Sulfate; Tris Base Sulfate; Tromethamine Sulfate; Tris Aminomethane Sulfate
EINECS	230-289-5

Quality Control

Our Trizma Sulfate is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity standards suitable for research and industrial applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White crystalline powder
Identification (IR)	Conforms
Assay (Titration)	≥ 99.0%
pH (1% Solution)	3.0 - 5.0
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Chloride (Cl)	≤ 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.