Description

(+)-Isoajmaline CAS NO 6989-79-3 is a specific stereoisomer of the ajmaline alkaloid, a compound of significant interest in pharmaceutical research and development. This high-purity standard is critical for analytical and pharmacological studies, particularly in the investigation of cardiac ion channel modulation. It serves as an essential reference material for researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors requiring precise chemical standards.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of ajmaline and related alkaloid-based drug substances.
• Cardiac Research: A key tool in preclinical studies investigating sodium channel blocking activity and antiarrhythmic mechanisms.
• Analytical Chemistry: Serves as a high-purity calibrant for method development and validation in techniques like HPLC, LC-MS, and NMR for alkaloid analysis.
• Biochemical Research: Employed in studies of plant alkaloid biosynthesis and for investigating interactions with specific biological receptors and enzymes.
• Quality Control: Essential for in-house quality testing and compliance in the manufacturing of related pharmaceutical intermediates or finished dosage forms.

Basic Information

Product Name	(+)-Isoajmaline
CAS No.	6989-79-3
Molecular Formula	C20H26N2O2
Molecular Weight	326.43 g/mol
Synonyms	Isoajmaline; (+)-Isoajmaline; (17R)-Ajmalan-17,21-diol; Isoajmalin; Isoajmaline (alkaloid); Ajmaline isomer; 17-Epiajmaline; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our (+)-Isoajmaline is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the stringent requirements for research and reference standards. A detailed Certificate of Analysis (COA) providing results for assay, related substances, and identification tests is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.