Description

1-o-Hexadecyl-2-Arachidonyl-Sn-Glycero-3-Phosphocholine is a synthetic, ether-linked phospholipid analog, specifically a platelet-activating factor (PAF) receptor antagonist. This compound is of significant value in biochemical and pharmacological research for studying cell signaling pathways, inflammation, and immune responses. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on cardiovascular, inflammatory, and immunological mechanisms.

Application

• Biochemical Research: Used as a high-purity reference standard and tool compound for studying PAF receptor-mediated signaling cascades.
• Pharmacological Studies: Serves as a key antagonist in vitro and in vivo models to investigate inflammation, anaphylaxis, and bronchoconstriction.
• Cell Biology: Employed in membrane biophysics research to understand the role of specific phospholipid structures in cell membrane function and integrity.
• Drug Discovery: Acts as a lead compound or molecular probe for the development of novel anti-inflammatory and anti-allergic therapeutics.
• Diagnostic Development: Utilized in the formulation of assay kits and reagents for detecting and quantifying PAF-related biological activity.

Basic Information

Item	Details
Product Name	1-o-Hexadecyl-2-Arachidonyl-Sn-Glycero-3-Phosphocholine
CAS No.	6931-56-2
Molecular Formula	C44H84NO7P
Molecular Weight	770.12 g/mol
Synonyms	Hexadecyl Arachidonyl Phosphatidylcholine; 1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine; PAF Antagonist C16:0/C20:4; 1-O-Hexadecyl-2-arachidonoyl-GPC; 1-Hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine; Glycerylphosphorylcholine, 1-O-hexadecyl-2-O-(5,8,11,14-eicosatetraenoyl)-; Platelet-Activating Factor Analog
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Arachidonyl-Sn-Glycero-3-Phosphocholine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation (by NMR, MS), and impurity profiles. We adhere to cGMP guidelines for research-grade biochemicals to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, ethanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.