Description

(13R,13Ar)-5,8,13,13A-Tetrahydro-2,3,9,10-Tetramethoxy-13-Methyl-6H-Dibenzo[A,G]Quinolizine CAS NO 6901-07-1 is a complex, high-purity alkaloid derivative belonging to the quinolizidine class. This compound is valued for its specific stereochemistry and functional groups, making it a critical advanced intermediate in sophisticated organic synthesis. It is primarily sought by pharmaceutical research and development organizations, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-cancer research.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Potential application as a ligand or inhibitor in enzymatic studies due to its complex alkaloid structure.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable compound for methodological development in asymmetric synthesis and total synthesis projects.

Basic Information

Product Name	(13R,13Ar)-5,8,13,13A-Tetrahydro-2,3,9,10-Tetramethoxy-13-Methyl-6H-Dibenzo[A,G]Quinolizine
CAS No.	6901-07-1
Molecular Formula	C22H27NO4
Molecular Weight	369.46 g/mol
Synonyms	13-Methyl-2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine; (13R,13aR)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine; A specific stereoisomer of tetrahydroberberine; Berbine, 2,3,9,10-tetramethoxy-13-methyl-, (13R,13aR)-; Dibenzo[a,g]quinolizine derivative
EINECS	Contact for details

Quality Control

Our (13R,13Ar)-5,8,13,13A-Tetrahydro-2,3,9,10-Tetramethoxy-13-Methyl-6H-Dibenzo[A,G]Quinolizine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and purity meet the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.