Description

Hypaconitine is a potent diterpenoid alkaloid derived from plants of the *Aconitum* genus, known for its significant biological activity. This high-purity reference standard is critical for analytical research, quality control, and pharmacological studies, ensuring precise identification and quantification in complex matrices. It is primarily utilized by research institutions, pharmaceutical development labs, and quality assurance departments in the herbal medicine and natural product sectors.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification and assay of aconite alkaloids in raw materials and finished herbal products.
• Biomedical Research: Used in pharmacological studies to investigate its effects on ion channels, neural pathways, and potential therapeutic applications.
• Analytical Chemistry: Essential for method development and validation in techniques like HPLC, LC-MS, and TLC for alkaloid profiling.
• Toxicology and Safety Testing: Employed as a marker compound in the analysis of toxicological samples and the assessment of product safety.
• Quality Control (QC) in Herbal Supplements: Used to monitor and control the levels of active and toxic alkaloids in commercial aconite-based preparations.
• Academic Research: Supports studies in phytochemistry, natural product isolation, and structural-activity relationship (SAR) analysis.

Basic Information

Product Name	Hypaconitine
CAS No.	6900-87-4
Molecular Formula	C33H45NO10
Molecular Weight	615.72 g/mol
Synonyms	Hypaconitine; 16-Ethyl-1,16,19-trimethoxy-4-(methoxymethyl)aconitane-3,8,10,11,14-pentaol 8-acetate 14-benzoate; 3-Deoxyaconitine; Jesaconitine B; Aconitane-3,8,10,11,14-pentaol, 16-ethyl-1,16,19-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate; (1α,3α,6α,14α,16β)-16-Ethyl-1,6,14-trimethoxy-4-(methoxymethyl)aconitane-3,8,10,11,13-pentaol 8-acetate 10-benzoate
EINECS	Contact for details

Quality Control

Our Hypaconitine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.