Description

(3β,20α)-1,2-Didehydro-2,7-Dihydro-11,17α-Dimethoxy-18β-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester is a complex yohimbane alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of bioactive molecules targeting neurological and cardiovascular systems. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthetic pathways for novel therapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing (GMP/GLP environments).
• Medicinal Chemistry Research: A vital compound for structure-activity relationship (SAR) studies to explore and optimize biological activity.
• Biochemical Tool: Employed in in vitro and in vivo studies to investigate interactions with specific receptors or enzymes.
• Academic Research: Used in university and institutional labs for fundamental research on alkaloid chemistry and pharmacology.
• Process Development: Acts as a standard for scaling up and optimizing synthetic routes in process chemistry.

Basic Information

Item	Details
Product Name	(3β,20α)-1,2-Didehydro-2,7-Dihydro-11,17α-Dimethoxy-18β-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester
CAS No.	6899-67-8
Molecular Formula	C33H38N2O9
Molecular Weight	606.67 g/mol
Synonyms	Methyl (3β,20α)-1,2-didehydro-2,7-dihydro-11,17α-dimethoxy-18β-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16β-carboxylate; 18β-Hydroxy-11,17α-dimethoxy-16β-(methoxycarbonyl)-3β,20α-yohimban-1,2-didehydro-2,7-diol 18-(3,4,5-trimethoxybenzoate); Rescinnamine Impurity; Rescinnamine Related Compound; Yohimbane Alkaloid Ester; Trimethoxybenzoyl Yohimbane Derivative
EINECS	Contact for details

Quality Control

Our high-purity product undergoes rigorous analytical testing to ensure identity, potency, and purity for research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing results from HPLC, NMR, and MS. Quality is managed in compliance with internal standards suitable for non-GMP R&D use. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.