Description

(2α,5α)-1-Acetyl-6β,17-Dimethoxyaspidofractinine-3β-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate or reference standard for the development of novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents or studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex indole alkaloid-based drug candidates targeting neurological or oncological pathways.
• Reference Standard: Used for analytical method development, validation, and quality control in the production of related active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic value.
• Academic Research: Utilized in university and institutional laboratories for studying alkaloid chemistry, biosynthesis, and novel synthetic methodologies.
• Process Chemistry Development: Serves as a model compound for scaling up and optimizing complex multi-step synthetic routes under GMP or non-GMP conditions.

Basic Information

Product Name	(2α,5α)-1-Acetyl-6β,17-Dimethoxyaspidofractinine-3β-Carboxylic Acid Methyl Ester
CAS No.	6878-72-4
Molecular Formula	C25H30N2O5
Molecular Weight	438.52 g/mol
Synonyms	Methyl (2α,5α)-1-acetyl-6β,17-dimethoxyaspidofractinine-3β-carboxylate; 1-Acetyl-6β,17-dimethoxyaspidofractinine-3β-carboxylic acid methyl ester; Aspidofractinine-3β-carboxylic acid, 1-acetyl-6β,17-dimethoxy-, methyl ester, (2α,5α)-; Kopsinine derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2α,5α)-1-Acetyl-6β,17-Dimethoxyaspidofractinine-3β-Carboxylic Acid Methyl Ester is produced under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support development from research to commercial scale with a commitment to reliable supply and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.