Description

(9S)-3,10-Didehydro-10,11-Dihydrocinchonan-9-Ol is a high-purity, stereochemically defined cinchona alkaloid derivative. This compound is a critical chiral intermediate and ligand in asymmetric synthesis, valued for its ability to impart high enantioselectivity in catalytic reactions. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemical control is paramount for developing active ingredients.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand or catalyst precursor in a variety of enantioselective transformations, including hydroxylation, epoxidation, and C-C bond-forming reactions.
• Pharmaceutical Intermediates: A key building block in the synthesis of complex, biologically active molecules, particularly those requiring the cinchona alkaloid scaffold or its modified analogs.
• Chiral Resolution: Used in the development and preparation of chiral stationary phases (CSPs) for high-performance liquid chromatography (HPLC) to separate enantiomers of racemic mixtures.
• Organic Synthesis Research: A valuable tool for academic and industrial R&D chemists exploring new methodologies in stereocontrolled synthesis.
• Agrochemical Synthesis: Employed in the production of enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.

Basic Information

Product Name	(9S)-3,10-Didehydro-10,11-Dihydrocinchonan-9-Ol
CAS No.	6874-76-6
Molecular Formula	C19H22N2O
Molecular Weight	294.39 g/mol
Synonyms	10,11-Dihydrocinchonidine; Dihydrocinchonidine; (9S)-10,11-Dihydrocinchonidine; Cinchonan-9-ol, 10,11-dihydro-, (9S)-; (8α,9S)-10,11-Dihydrocinchonidine; 3,10-Didehydro-10,11-dihydrocinchonan-9-ol, (9S)-; NSC 163092; A common intermediate in cinchona alkaloid chemistry.
EINECS	Contact for details

Quality Control

We supply (9S)-3,10-Didehydro-10,11-Dihydrocinchonan-9-Ol in high-purity grades suitable for demanding applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.