Description

(12α,16α)-9,10-[Methylenebis(Oxy)]Galanthan is a complex, high-purity galanthamine derivative characterized by its unique methylenebis(oxy) bridge. This compound is valued for its potential as a key synthetic intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought by research institutions and pharmaceutical companies focused on neuroscience, alkaloid chemistry, and the development of novel acetylcholinesterase inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel galanthamine analogs and related bioactive compounds.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Neuroscience Research: Investigated for its biological activity and potential pharmacological effects in academic and industrial R&D settings.
• Alkaloid Chemistry Studies: Employed as a model compound in studies of Amaryllidaceae alkaloid structure-activity relationships and synthetic pathways.
• Process Chemistry: Utilized in the development and scaling of synthetic routes for complex natural product derivatives.

Basic Information

Product Name	(12α,16α)-9,10-[Methylenebis(Oxy)]Galanthan
CAS No.	6871-57-4
Molecular Formula	C18H21NO5
Molecular Weight	331.36 g/mol
Synonyms	9,10-Methylenedioxygalanthan; (12α,16α)-9,10-Methylenedioxygalanthan; Galanthan, 9,10-methylenedioxy-; 9,10-(Methylenedioxy)galanthan; Galanthamine derivative with methylenedioxy bridge; Lycoramine derivative; Amaryllidaceae alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (12α,16α)-9,10-[Methylenebis(Oxy)]Galanthan is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect the product from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.