Description

(20α)-16,17-Didehydroyohimban-16-Carboxylic Acid Methyl Ester is a high-purity, specialized indole alkaloid derivative of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the research and development of novel pharmaceutical agents, particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of yohimbine analogs and other indole-based therapeutic compounds.
• Neurological Research: Used in the development of ligands and probes for studying adrenergic and serotonergic receptor systems.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Employed as an analytical standard in HPLC and LC-MS methods for quality control and metabolic studies.
• Chemical Synthesis: Utilized in multi-step organic syntheses to construct complex natural product frameworks.

Basic Information

Product Name	(20α)-16,17-Didehydroyohimban-16-Carboxylic Acid Methyl Ester
CAS No.	6871-14-3
Molecular Formula	C21H24N2O3
Molecular Weight	352.43 g/mol
Synonyms	Methyl (20α)-16,17-didehydroyohimban-16-carboxylate; 16-Carbomethoxy-16,17-didehydro-20α-yohimbane; 16β-Carbomethoxy-δ16,17-20α-yohimbane; Yohimban-16-carboxylic acid, 16,17-didehydro-, methyl ester, (20α)-; Methyl 16,17-didehydroyohimban-16-carboxylate; 16β-Methoxycarbonyl-δ16,17-20α-yohimbane; 16β-Carbonmethoxy-δ16,17-20α-yohimbane
EINECS	Contact for details

Quality Control

Our (20α)-16,17-Didehydroyohimban-16-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.