Description

Jacobine is a pyrrolizidine alkaloid of significant interest in research and development. This compound is valued for its role as a reference standard and a key intermediate in the synthesis of more complex molecules. It is primarily sought after by the pharmaceutical, biotechnology, and agrochemical industries for applications in analytical chemistry, toxicology studies, and the development of novel active ingredients.

Application

• Pharmaceutical Research: Used as a reference standard and analytical marker in the study of pyrrolizidine alkaloid toxicity and metabolism.
• Biochemical Studies: Serves as a crucial intermediate or starting material in the synthesis of specialized chemical probes and inhibitors.
• Agrochemical Development: Investigated as a potential lead compound or biosynthetic precursor for novel plant protection agents.
• Analytical Chemistry: Employed in method development and validation for the detection and quantification of alkaloids in complex matrices.
• Toxicology & Safety Assessment: Essential for conducting safety evaluations and establishing regulatory limits for natural contaminants in food and herbal products.

Basic Information

Product Name	Jacobine
CAS No.	6870-67-3
Molecular Formula	C18H25NO6
Molecular Weight	351.40 g/mol
Synonyms	Jacobine; (-)-Jacobine; (1R,7aR)-1,2,3,5,6,7,7a,8-Octahydro-1-hydroxy-8-methyl-7-methylene-5-oxopyrrolizine-1,6-dicarboxylic acid 6-methyl ester; NSC 89364; Pyrrolizidine alkaloid Jacobine
EINECS	Contact for details

Quality Control

Every batch of Jacobine is subjected to rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent in-house quality standards, with testing typically including HPLC for assay and related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.